This lotion is indicated for the treatment of scabies and pruritus.
Permethrin is a pyrethroid pediculocide and scabicide. It causes paralysis and death of the pest by inhibiting sodium ion influx through nerve cell membrane channels delaying repolarisation.
Crotamiton has scabicidal and antipruritic action against Sarcoptes scabei. It is an effective pediculocide as well.